Inhalation Friday, July 25, 2014
Skip Navigation LinksHome) Item Details
Inhalation is the only technical publication devoted exclusively to readers involved in development and production of pulmonary or nasal delivered pharmaceuticals.
Technical Articles
   
Item Details:
Publication Date: 02/2008
Pages: 3
Medium:
PDF Format
US:
$7.50
Recommended Item:
Inverse gas chromatography

A novel finite dilution IGC technique for the physicochemical characterization and optimization of dry powder inhalation formulations.

In the October 2007 issue of Inhalation, Andrew Otte and M. Teresa Carvajal presented a comprehensive overview of solid surface energy principles and applied measurement techniques for DPI formulations, including infinite dilution inverse gas chromatography (IGC). This follow-up article focuses specifically on the use of IGC for the determination of surface energy as a function of processing conditions for both API and excipient carrier molecules used in inhalable formulations and introduces a novel finite dilution approach that offers a unique new method of profiling surface heterogeneity, which plays a major role in drug-carrier interactions. This extremely sensitive approach provides data of unparalleled specificity that can benefit every stage of the DPI formulation process.

To read this entire article:

You may purchase this article now for personal use. Simply click the Buy Item button above, enter your payment details, and download the article. It will be available to you for 7 days for viewing, printing, or saving for future reference. All articles are copyrighted by CSC Publishing, Inc. and cannot be used for commercial purposes without express permission in writing from the Publisher. This includes but is not limited to: web posting, printing, or sharing via email.

Security:

Your payment information is forwarded in an encrypted form, using 40- or 128-bit Secure Socket Layer technology, only to our payment gateway (Authorize.net) for processing.

Acrobat:

To view an article, you must have Acrobat Reader installed on your computer. Click on the icon to download Acrobat Reader free of charge.

HyperLink
      Copyright 2014, CSC Publishing Inc. ALL Rights Reserved * Privacy policy