Cascade Impactors
Theory, design, and practical information for optimal testing.
Cascade impaction is the only particle size measurement technique that can differentiate API from other components in a formulation, so this technique is the key analytical method for both development and quality assurance of inhaled products; all of the major pharmaceutical regulatory agencies specify the use of cascade impactors for these analyses. Accurate testing is critical, and impactor testing requires substantial investments of time and money. A basic understanding of the design and operation of cascade impactors and their operating parameters can help achieve optimum performance in return.