Impact of capsule selection on formulation stability in dry powder inhalers (DPIs)
An examination of differences between gelatin and HPMC capsules and their respective contributions to DPI formulations.
With the growing number of dry powder inhalers, it has been well recognized that a unique set of requirements related to these formulations exist separately from traditional, solid-dose, oral formulations. These requirements have implications for devices, containers and manufacturing
equipment, such that a successful product will ultimately be the partnership of these. This article will
discuss the unique qualities associated with a dry powder inhaler formulation and ways to streamline DPI formulation efforts by the choice of capsule.