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Inhalation is the only technical publication devoted exclusively to readers involved in development and production of pulmonary or nasal delivered pharmaceuticals.
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Publication Date: 04/2011
Pages: 4
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$7.50
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Significant restriction of the delivered dose uniformity criteria in the revised USP Chapter for Aerosols <601>
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Thixotropic sprays: Popular with patients, challenging for developers

Analysis of particle size and morphology provides essential information for formulators developing thixotropic suspensions.

Confirming particle size and ensuring that suspended drug particles are evenly dispersed within a thixotropic solution creates a number of challenges. This article will discuss the issues that formulators have to address when creating a thixotrophic suspension and the types of analyses that are available to determine the extent to which the nasal spray has been optimized.

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