This Month’s Focus: Devices
Penetration enhancers and mucoadhesives in liquid nasal spray formulations
Some commercially available liquid nasal spray formulations include excipients that can act as penetration enhancers or mucoadhesives. They may thereby provide the benefit of increasing contact/residence time in the nasal cavity or increasing absorption of drug molecules by enhancing permeability through nasal mucosal membranes. This review may assist readers in considering the utility of various penetration enhancers and mucoadhesives for use in research and development.
Propellant and formulation properties for next-generation pMDIs: Measurement, representation and prediction
In this article, the fundamental thermophysical properties that control the complex internal flow and aerosol formation process in a pMDI will be examined, from the perspective of their measurement, representation and prediction. Activity coefficient models that enable simultaneous description and prediction of important formulation thermophysical properties will also be presented. The performance of these models is demonstrated using existing data for HFA134a/ethanol mixtures, to show their potential application alongside experimental property data collection involving future propellants.
Cross-Industry Organizations: Respiratory Drug Delivery 2022: Bringing the respiratory world together in person and virtually
RDD 2022 will be held in person in Orlando, Florida, May 1-5, 2022. However, the best ways of interacting will allow delegates who are not yet ready, willing or able to travel to the US to participate. Further, if an in-person conference becomes impractical for any reason, the organizers are well equipped to revert to a virtual event.
Back Pages: Food allergies increase challenges for people facing food insecurity. Is food insecurity associated with asthma? Study results conflict
For millions in the US newly experiencing food insecurity due to the COVID-19 pandemic, those with food allergies are facing “a particular crisis” in that most charitable and government food programs offer limited options that are safely edible. The Food Equality Initiative and Porchlight Community Services are two organizations that support clients with food allergies. Multiple studies have been conducted to determine whether food insecurity is associated with asthma and, if so, to evaluate the extent of such a relationship. However, results are conflicting.
Previewing the DDL2021 Virtual Conference
Due to COVID-19, Drug Delivery to the Lungs 2021 (DDL2021) will be presented live online, December 8-10, replacing the in-person event originally planned for the same dates in Edinburgh, UK. Conference highlights will include scientific presentations, a sponsor exhibition, awards and the New Researcher Network Discussion Forum. Content will be presented in a single stream, enabling attendees to view all of the conference’s live content.
Weighing in on NGI gravimetric cups
Idiopathic pulmonary fibrosis: An opportunity for more inhaled therapies
Cross-industry organizations: PQRI
January: Reference and Buyer’s Resource
February: Product Development/ Contract Testing
June: Nasal Delivery/Nebulizers
August: Particle Characterization
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