• Publication Date: 12/01/2015
  • Author(s):
    Díez, Fernando Jones, Brian E.
  • Organization(s):
    Qualicaps Europe
  • Article Type: Technical Articles
  • Subjects: Capsules and Blisters, Devices and Components, Product Development/Formulation
HPMC capsules used in DPIs can provide key advantages in inhalation parameters.

DPIs offer ease of coordination with the respiratory cycle compared to pMDIs and a reduced amount of drug trapped in the oropharynx. In addition, devices that do not use chlorofluorocarbon propellants are better for the environment. Within the sphere of DPIs, HPMC-capsule-based DPIs are a compelling alternative due to capsule properties of puncturing, powder aerosolization, control of internal capsule surface and performance with low-moisture contents.

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