Using laser diffraction and morphological imaging to examine aerosolization performance of carrier-free inhalation powders.
A combination of two complementary characterization techniques, laser diffraction and image analysis, delivers data on particle size and morphology that can accelerate and optimize the development of carrier-free dry powders by improving understanding of how a process like particle coating affects the dispersion characteristics of the formulation. Laser diffraction enables the examination of powder entrainment and dispersion, while image analysis enables the study of powder structure before and after delivery.