- Author(s):
- Organization(s):
Clearmarsh Ltd. Clement Clarke International Ltd.
The earliest reference to therapeutic dry powder inhalation may also be the earliest reference to “engineered particles,” dating from 1849, in London. Since the 1950s, the pace of dry powder inhaler (DPI) development has been astounding.
The authors provide a brief history of dry powder inhalers then discuss considerations for future development such as formulation, dose storage, moisture protection and metering, de-aggregative processes, counters, the environment, patient considerations and non-respiratory indications.