• Home /
  • Articles /
  • Effect of conditioning on rat lung function measurements and implications for exposure and dose estimation of inhaled drugs
← Back to search results

Effect of conditioning on rat lung function measurements and implications for exposure and dose estimation of inhaled drugs

  • Publication Date: 02/01/2017
  • Author(s):
    Gumbleton, Mark Paul, Graham R. Somers, Graham I.
  • Organization(s):
    Cardiff University GlaxoSmithKline
  • Article Type: Technical Articles
  • Subjects: Instruments, Product Development/Formulation, Testing, Validation, and Regulatory Compliance
Measurement of minute volume by head-out plethysmography may provide a tool for refining inhalation exposure, understanding dosing anomalies and effects on dosimetry.

Measurement of minute volume by head-out plethysmography may provide a tool for refining inhalation exposure and understanding dosing anomalies and potential effects on dosimetry associated with test substance properties, such as respiratory pharmacology or irritancy.

Download PDF