• Publication Date: 10/01/2009
  • Author(s):
    Chan, Hak-Kim Hoe, Susan Traini, Daniela Young, Paul M.
  • Organization(s):
    University of Sydney
  • Article Type: Technical Articles
  • Subjects: Instruments, Particle Characterization
An improved methodology for characterizing electrostatic charge distribution across the entire particle size range of an aerosolized inhalation formulation.

An ideal instrument for characterizing the charges on aerosol particles would provide data showing the distribution of charge across the particle size distribution at patient relevant flow rates. To meet this need, the University of Sydney has developed a system using a modified Next Generation Pharmaceutical Impactor (NGI). The electrostatic NGI (eNGI) represents a major advance in the ability of formulators to obtain information about charges generated in pharmaceutical aerosols.

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