Treatment for multidrug-resistant tuberculosis requires lengthy and complicated regimens. These include oral, poorly absorbed, toxic drugs and daily intra-muscular injections of high quantities of parenteral agents, for a duration of several months. Reformulating such medications into dry powders suitable for inhalation and deposition to the deep lung shows promise. Indications are that healthcare workers would be in favor of such an option.
Inhaled therapies for tuberculosis: A viable approach for spray-dried drugs delivered by handheld dry powder inhaler
Inhalation may enhance efficacy and reduce adverse effects compared to oral and parenteral therapies.