• Publication Date: 12/01/2020
  • Author(s):
    Suman, Julie D.
  • Organization(s):
    Next Breath Aptar Pharma
  • Article Type: Technical Articles
  • Subjects: Device Design, Devices and Components, Industry Issues and Trends, Nasal Delivery, Product Development/Formulation
Nasal drug delivery has been a mainstay for local indications since the late 1900s. Delivery systems have evolved from less-precise dosing systems to sophisticated devices designs able to protect formulations and achieve reliable dosing. Further advances are anticipated, including connected applications. In addition, intranasal administration has become a trusted route for rescue medications. In the future, unmet needs may also be addressed in niche patient populations.

The author provides a brief history of nasal delivery devices and their applications then look to potential uses in the future. Article topics include: device platforms, locally acting products, vaccines, systemic nasal drug delivery, patient considerations, regulatory considerations and future opportunities. In addition, the article includes a table listing samples of US FDA-approved nasal products introduced between 1965 and 2020.

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