• Publication Date: 06/01/2017
  • Author(s):
    Fishler, Rami Sznitman, Josué
  • Organization(s):
    Department of Biomedical Engineering, Technion—Israel Institute of Technology
  • Article Type: Technical Articles
  • Subjects: Instruments, Particle Characterization, Product Development/Formulation, Testing, Validation, and Regulatory Compliance
A simple, optical method for estimating APSDs through direct measurement of particle settling velocities using image-based analysis and particle tracking techniques.

A simple, optical method provides accurate and fast measurements (approximately 1 minute) with few sources of bias due to specific device design choices or operating conditions. A proof-of-concept for the method is demonstrated by measuring APSDs for widely available commercial dry powder inhalers, then comparing the results with previously published data from cascade impactors and the Aerodynamic Particle Sizer.

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