• Publication Date: 10/01/2011
  • Author(s):
    Daintree, Lyn York, Peter
  • Organization(s):
    CrystecPharma, Institute of Pharmaceutical Innovation, University of Bradford
  • Article Type: Technical Articles
  • Subjects: Industry Issues and Trends, Particle Manufacturing, Product Development/Formulation
Supercritical fluid anti-solvent technologies offer a single step, efficient route for producing inhalation particles

Design of drug particles for inhalation medicines is an important factor in providing high quality, efficacious and safe medicines. Various approaches for generating micron sized drug particles required are summarized here and the key benefits of a controllable, single step, efficient process highlighted. The antisolvent supercritical fluid method is now well understood, proven at scale and operating at cGMP.

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