Particle engineering by practical and scalable, intensive, mechanical, dry coating processes to develop highly efficient dry powder inhaler formulations

Developing DPIs for new indications with challenging doses, such as antibiotics, require the products to possess high aerosolization efficiency and superior performance consistency. To achieve this, particle engineering appears necessary. Dry coating equipment appears to be highly effective, simple, scalable and economical. It can also complement current industrial manufacturing processes. Therefore, this approach appears to be a promising strategy for design and manufacture of next generation, high performance DPI products.