Over the past decades, important progress has been achieved through the introduction of new capsule types and advanced particle engineering. A range of HPMC capsules with distinct properties as well as customizable specifcations have broadened the design space for cDPI systems. The use of spray-drying technology for advanced particle engineering allows the delivery of much higher drug doses and also enables the formulation and delivery of biological compounds via the pulmonary route.
Progress in particle engineering science: Towards advanced dry powder inhalation systems
Insight into characteristics of HPMC capsules and development of engineered particles to achieve targeted product characteristics and performance criteria.