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Spray pattern: A rapid and sensitive early development tool for respiratory drug products

  • Publication Date: 10/01/2017
  • Author(s):
    Chauhan, Heli L’Ecuyer, Tim Leveille, Chip Liao, Linda (Lingzhi) Liu-Cordero, Shau Neen Newcomb, Alyssa
  • Organization(s):
    Proveris Scientific Corporation
  • Article Type: Technical Articles
  • Subjects: Device Design, Devices and Components, Instruments, Product Development/Formulation, Testing, Validation, and Regulatory Compliance
Utilizing spray performance measurements to accelerate OINDP development.

Spray pattern and plume geometry have long been established as required tests for orally inhaled and nasal drug product (OINDP) characterization. Furthermore, these tests are important indicators of aerosolization, spray performance and subsequent bioavailability (BA) of the delivered drug.

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