This article discusses principles of capsule puncturing then presents a comparative study of puncturing forces in gelatin and HPMC capsules. There are multiple applications in which the testing presented here could be beneficial, to capsule manufacturers for their quality control measures, to manufacturers of capsule-based inhalation products and, by extension, to patients utilizing those medications. These options all involve the concept of consistent force necessary for puncturing capsules in an inhalation device.
Testing and comparison of puncturing forces for gelatin and HPMC inhalation capsules
Data on capsule puncturing forces and consistency in capsule puncturing could provide benefits for capsule manufacturers, developers of capsule-based inhalers and patients.