• Publication Date: 06/01/2011
  • Author(s):
    Scherließ, Regina
  • Organization(s):
    Christian Albrecht University
  • Article Type: Technical Articles
  • Subjects: Device Design, Nasal Delivery, Product Development/Formulation
A nasal cast model can be used for in vitro characterization and optimization of nasal dry powder formulations

For the localization of formulation deposition within the nasal cavity, a nasal replica model can be used. Models in use are cadaver casts or are made from CT scan data or similar data of a vital nose. Casts representing a vital nose are preferred, although casts always represent an individual’s nose with its particular dimensions, age, gender and other characteristics that may influence the deposition.

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