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The European Pharmaceutical Aerosol Group (EPAG) was founded in 1999 based on the premise that “industry is able and stronger when it works together to deliver much-needed orally inhaled and nasal drug products (OINDPs).” EPAG’s work continues to support that premise today. This article provides a look at their recent activities as well as their […]

The Association of Inhalation Toxicologists (AIT) presented a workshop at the 2023 Drug Delivery to the Lungs Conference. The focus was on methods used for in vitro toxicity screening, in vivo study designs, toxicological endpoints and regulatory toxicology. The workshop also covered technical aspects of the generation, characterization and dosimetry of aerosols in toxicology studies. […]

This article provides a brief history of the formation of The European Pharmaceutical Aerosol Group (EPAG), including its constitution, objectives, structure, influence, publications and input to regulatory guidance documents. A list of the organization’s publications and references since 2000 is also included. The large body of published articles coming from EPAG, together with the influence […]

The earliest reference to therapeutic dry powder inhalation may also be the earliest reference to “engineered particles,” dating from 1849, in London. An initial article looks at the history of dry powder inhalers, including devices and formulations, and discusses considerations for future DPIs. Then an interview takes a new look at current challenges and opportunities […]

A large gap exists between the relatively straightforward robust methods in the pharmacopeias, developed primarily for product release, and the more elaborate approaches to assist in understanding how inhalers are likely to perform in the hands of the patient or caregiver. The authors propose that there is a middle way forward and believe it is […]

The author suggests opportunities exist in treating additional diseases, getting involved with patients, determining aerodynamic particle size distribution, managing oropharyngeal deposition, improving nasal delivery and targeting orally inhaled products with narrow therapeutic indices.

IPAC-RS hopes users will choose topics of interest and that each module will provide an engaging lesson in a manageable format. New modules will be made available online as they are completed.

Follow Savion, age 10, on a journey with the Medikidz superheroes from Mediland, a living, moving planet like the human body. The characters are designed to be fun and appealing to young people so that entertainment and education can happen in tandem.

This online museum helps ensure that some remarkably clever, early ideas for inhalation therapy are not forgotten. The earliest DPI reference now appears to be 1848, predating the Spinhaler by more than 100 years.

In Hawai’i, volcanically-generated smog can result in poor air quality poor air quality comparable with that of Los Angeles or London, UK on a hot summer’s day. About 4.4% (age-adjusted = 4.2%) of Hawai’i residents have been told by a healthcare professional they have COPD. A 2010 report noted that social, economic and demographic variation, […]