A case study reviewing inhalation devices. Capsule-based devices in particular, offer many benefits to patients in terms of precise dosing, ease of use and dose visibility. For manufacturers, capsule-based DPI technology provides greater freedom to innovate and differentiate their products.
This case study examines how Experic worked with a mid-sized pharmaceutical company to address the challenges hindering the advancement of their product and illustrates the importance of introducing filling studies during formulation development to avoid costly delays and reformulation.
Within the sphere of DPIs, HPMC-capsule-based DPIs are a compelling alternative due to capsule properties of puncturing, powder aerosolization, control of internal capsule surface and performance with low-moisture contents.
Set against the backdrop of environmental concerns over HFC propellants used in pressurised metered-dose inhalers, this article presents evidence supporting the adoption of dry-powder inhalers as an attractive alternative.